889 search results - page 88 / 178 » General Conclusions |
142
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BMCBI
2008
15 years 4 months ago
2008
Background: The traditional (unweighted) k-means is one of the most popular clustering methods for analyzing gene expression data. However, it suffers three major shortcomings. It...
125
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BMCBI
2007
15 years 4 months ago
2007
Background: Genome-wide association studies of common diseases for common, low penetrance causal variants are underway. A proportion of these will alter protein sequences, the mos...
124
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BMCBI
2007
15 years 4 months ago
2007
Background: Pre-processing methods for two-sample long oligonucleotide arrays, specifically the Agilent technology, have not been extensively studied. The goal of this study is to...
161
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BMCBI
2007
15 years 4 months ago
2007
Background: An important goal of comparative genomics is the identification of functional elements through conservation analysis. Phylo-HMM was recently introduced to detect conse...
152
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BMCBI
2005
15 years 4 months ago
2005
Background: Recent advances in molecular biology techniques provide an opportunity for developing detailed mathematical models of biological processes. An iterative scheme is intr...