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BMCBI
2006
126views more  BMCBI 2006»
15 years 4 months ago
Effect of data normalization on fuzzy clustering of DNA microarray data
Background: Microarray technology has made it possible to simultaneously measure the expression levels of large numbers of genes in a short time. Gene expression data is informati...
Seo Young Kim, Jae Won Lee, Jong Sung Bae
BMCBI
2010
119views more  BMCBI 2010»
15 years 1 months ago
The INTERPRET Decision-Support System version 3.0 for evaluation of Magnetic Resonance Spectroscopy data from human brain tumour
Background: Proton Magnetic Resonance (MR) Spectroscopy (MRS) is a widely available technique for those clinical centres equipped with MR scanners. Unlike the rest of MR-based tec...
Alexander Pérez-Ruiz, Margarida Julià...
BMCBI
2010
109views more  BMCBI 2010»
15 years 4 months ago
Free energy estimation of short DNA duplex hybridizations
Background: Estimation of DNA duplex hybridization free energy is widely used for predicting cross-hybridizations in DNA computing and microarray experiments. A number of software...
Dan C. Tulpan, Mirela Andronescu, Serge Leger
BMCBI
2010
138views more  BMCBI 2010»
15 years 4 months ago
A model-independent approach to infer hierarchical codon substitution dynamics
Background: Codon substitution constitutes a fundamental process in molecular biology that has been studied extensively. However, prior studies rely on various assumptions, e.g. r...
Olof Görnerup, Martin Nilsson Jacobi
BMCBI
2006
102views more  BMCBI 2006»
15 years 4 months ago
Predicting population coverage of T-cell epitope-based diagnostics and vaccines
Background: T cells recognize a complex between a specific major histocompatibility complex (MHC) molecule and a particular pathogen-derived epitope. A given epitope will elicit a...
Huynh-Hoa Bui, John Sidney, Kenny Dinh, Scott Sout...