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BMCBI
2005
104views more  BMCBI 2005»
15 years 4 months ago
An integrated approach of immunogenomics and bioinformatics to identify new Tumor Associated Antigens (TAA) for mammary cancer i
Background: Neoplastic transformation is a multistep process in which distinct gene products of specific cell regulatory pathways are involved at each stage. Identification of ove...
Federica Cavallo, Annalisa Astolfi, Manuela Iezzi,...
BMCBI
2007
134views more  BMCBI 2007»
15 years 4 months ago
Nearest Neighbor Networks: clustering expression data based on gene neighborhoods
Background: The availability of microarrays measuring thousands of genes simultaneously across hundreds of biological conditions represents an opportunity to understand both indiv...
Curtis Huttenhower, Avi I. Flamholz, Jessica N. La...
KI
2008
Springer
15 years 4 months ago
Can Argumentation Help AI to Understand Explanation?
ed from context by seeing an explanation inferentially, much in the same way that early expert systems saw an explanation as chaining of inferences. This approach omitted, for the ...
Doug Walton
BMCBI
2010
99views more  BMCBI 2010»
15 years 4 months ago
Shared probe design and existing microarray reanalysis using PICKY
Background: Large genomes contain families of highly similar genes that cannot be individually identified by microarray probes. This limitation is due to thermodynamic restriction...
Hui-Hsien Chou
BMCBI
2006
117views more  BMCBI 2006»
15 years 4 months ago
The Cluster Variation Method for Efficient Linkage Analysis on Extended Pedigrees
Background: Computing exact multipoint LOD scores for extended pedigrees rapidly becomes infeasible as the number of markers and untyped individuals increase. When markers are exc...
Cornelis A. Albers, Martijn A. R. Leisink, Hilbert...