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BMCBI
2006
151views more  BMCBI 2006»
15 years 4 months ago
Machine learning and word sense disambiguation in the biomedical domain: design and evaluation issues
Background: Word sense disambiguation (WSD) is critical in the biomedical domain for improving the precision of natural language processing (NLP), text mining, and information ret...
Hua Xu, Marianthi Markatou, Rositsa Dimova, Hongfa...
BMCBI
2006
137views more  BMCBI 2006»
15 years 4 months ago
A maximum likelihood framework for protein design
Background: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, thi...
Claudia L. Kleinman, Nicolas Rodrigue, Céci...
BMCBI
2006
92views more  BMCBI 2006»
15 years 4 months ago
A jumping profile Hidden Markov Model and applications to recombination sites in HIV and HCV genomes
Background: Jumping alignments have recently been proposed as a strategy to search a given multiple sequence alignment A against a database. Instead of comparing a database sequen...
Anne-Kathrin Schultz, Ming Zhang, Thomas Leitner, ...
BMCBI
2006
169views more  BMCBI 2006»
15 years 4 months ago
Machine learning techniques in disease forecasting: a case study on rice blast prediction
Background: Diverse modeling approaches viz. neural networks and multiple regression have been followed to date for disease prediction in plant populations. However, due to their ...
Rakesh Kaundal, Amar S. Kapoor, Gajendra P. S. Rag...
135
Voted
BMCBI
2006
144views more  BMCBI 2006»
15 years 4 months ago
methBLAST and methPrimerDB: web-tools for PCR based methylation analysis
Background: DNA methylation plays an important role in development and tumorigenesis by epigenetic modification and silencing of critical genes. The development of PCR-based methy...
Filip Pattyn, Jasmien Hoebeeck, Piet Robbrecht, Ev...
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