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» Generalization Methods in Bioinformatics
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145
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CSB
2002
IEEE
103views Bioinformatics» more  CSB 2002»
15 years 9 months ago
Protein-Based Analysis of Alternative Splicing in the Human Genome
Understanding the functional significance of alternative splicing and other mechanisms that generate RNA transcript diversity is an important challenge facing modern-day molecular...
Ann E. Loraine, Gregg A. Helt, Melissa S. Cline, M...
CSB
2002
IEEE
109views Bioinformatics» more  CSB 2002»
15 years 9 months ago
Towards Automatic Clustering of Protein Sequences
Analyzing protein sequence data becomes increasingly important recently. Most previous work on this area has mainly focused on building classification models. In this paper, we i...
Jiong Yang, Wei Wang 0010
DNA
2001
Springer
15 years 9 months ago
The Fidelity of the Tag-Antitag System
In the universal DNA chip method, target RNAs are mapped onto a set of DNA tags. Parallel hybridization of these tags with an indexed, complementary antitag array then provides an ...
John A. Rose, Russell J. Deaton, Masami Hagiya, Ak...
WABI
2001
Springer
134views Bioinformatics» more  WABI 2001»
15 years 9 months ago
Comparing Assemblies Using Fragments and Mate-Pairs
Using current technology, large consecutive stretches of DNA (such as whole chromosomes) are usually assembled from short fragments obtained by shotgun sequencing, or from fragment...
Daniel H. Huson, Aaron L. Halpern, Zhongwu Lai, Eu...
108
Voted
WABI
2001
Springer
15 years 9 months ago
A Chemical-Distance-Based Test for Positive Darwinian Selection
There are very few instances in which positive Darwinian selection has been convincingly demonstrated at the molecular level. In this study, we present a novel test for detecting p...
Tal Pupko, Roded Sharan, Masami Hasegawa, Ron Sham...