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BMCBI
2007
116views more  BMCBI 2007»
15 years 6 months ago
Clustering protein environments for function prediction: finding PROSITE motifs in 3D
Background: Structural genomics initiatives are producing increasing numbers of threedimensional (3D) structures for which there is little functional information. Structure-based ...
Sungroh Yoon, Jessica C. Ebert, Eui-Young Chung, G...
BMCBI
2005
116views more  BMCBI 2005»
15 years 6 months ago
Dynamic covariation between gene expression and proteome characteristics
Background: Cells react to changing intra- and extracellular signals by dynamically modulating complex biochemical networks. Cellular responses to extracellular signals lead to ch...
Mansour Taghavi Azar Sharabiani, Markku Siermala, ...
LOGCOM
2007
130views more  LOGCOM 2007»
15 years 6 months ago
A Logic for Concepts and Similarity
Categorisation of objects into classes is currently supported by (at least) two ‘orthogonal’ methods. In logic-based approaches, classifications are defined through ontologi...
Mikhail Sheremet, Dmitry Tishkovsky, Frank Wolter,...
BMCBI
2004
96views more  BMCBI 2004»
15 years 6 months ago
A hybrid clustering approach to recognition of protein families in 114 microbial genomes
Background: Grouping proteins into sequence-based clusters is a fundamental step in many bioinformatic analyses (e.g., homology-based prediction of structure or function). Standar...
Timothy J. Harlow, J. Peter Gogarten, Mark A. Raga...
BMCBI
2004
229views more  BMCBI 2004»
15 years 6 months ago
Automatic annotation of protein motif function with Gene Ontology terms
Background: Conserved protein sequence motifs are short stretches of amino acid sequence patterns that potentially encode the function of proteins. Several sequence pattern search...
Xinghua Lu, Chengxiang Zhai, Vanathi Gopalakrishna...