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BMCBI
2008
127views more  BMCBI 2008»
15 years 7 months ago
Gene and pathway identification with Lp penalized Bayesian logistic regression
Background: Identifying genes and pathways associated with diseases such as cancer has been a subject of considerable research in recent years in the area of bioinformatics and co...
Zhenqiu Liu, Ronald B. Gartenhaus, Ming Tan, Feng ...
BMCBI
2007
146views more  BMCBI 2007»
15 years 7 months ago
Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data
Background: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental ...
Xiangdong Liu, Walter J. Jessen, Siva Sivaganesan,...
BMCBI
2007
113views more  BMCBI 2007»
15 years 7 months ago
CoryneRegNet 4.0 - A reference database for corynebacterial gene regulatory networks
Background: Detailed information on DNA-binding transcription factors (the key players in the regulation of gene expression) and on transcriptional regulatory interactions of micr...
Jan Baumbach
BMCBI
2010
127views more  BMCBI 2010»
15 years 7 months ago
PeptideMine - A webserver for the design of peptides for protein-peptide binding studies derived from protein-protein interactom
Background: Signal transduction events often involve transient, yet specific, interactions between structurally conserved protein domains and polypeptide sequences in target prote...
Khader Shameer, Lalima L. Madan, Shivamurthy Veera...
BMCBI
2008
169views more  BMCBI 2008»
15 years 7 months ago
A comprehensive comparison of random forests and support vector machines for microarray-based cancer classification
Background: Cancer diagnosis and clinical outcome prediction are among the most important emerging applications of gene expression microarray technology with several molecular sig...
Alexander R. Statnikov, Lily Wang, Constantin F. A...