Motivation: In many proteins, helix-helix interactions can be critical to establishing protein conformation (folding) and dynamics, as well as determining associations between pro...
Anne E. Counterman Burba, Ursula Lehnert, Eric Z. ...
Motivation: Genetic analysis of HIV-1 is important not only for vaccine development, but also to guide treatment strategies, track the emergence of new viral variants and ensure t...
Tulio de Oliveira, Koen Deforche, Sharon Cassol, M...
A key issue in supervised protein classification is the representation of input sequences of amino acids. Recent work using string kernels for protein data has achieved state-of-t...
Jason Weston, Christina S. Leslie, Eugene Ie, Deng...
Motivation: The high content of repetitive sequences in the genomes of many higher eukaryotes renders the task of annotating them computationally intensive. Presently, the only wi...
Nikoleta Juretic, Thomas E. Bureau, Richard M. Bru...
Motivation: Net Nearest Neighbor Analysis (NNNA) measures a previously unexamined aspect of dinucleotide frequency--the non-compensated, non-repetitive dinucleotides in a sequence...