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BIBE
2007
IEEE
110views Bioinformatics» more  BIBE 2007»
15 years 9 months ago
Discrete Methods for Association Search and Status Prediction in Genotype Case-Control Studies
Abstract—Recent improvements in high-throughput genotyping technology make possible genome-wide association studies and status prediction (classification) for common complex dis...
Dumitru Brinza, Alexander Zelikovsky
CSB
2004
IEEE
131views Bioinformatics» more  CSB 2004»
15 years 7 months ago
Improved Fourier Transform Method for Unsupervised Cell-Cycle Regulated Gene Prediction
Motivation: Cell-cycle regulated gene prediction using microarray time-course measurements of the mRNA expression levels of genes has been used by several researchers. The popular...
Karuturi R. Krishna Murthy, Liu Jian Hua
BMCBI
2008
178views more  BMCBI 2008»
15 years 3 months ago
A discriminative method for protein remote homology detection and fold recognition combining Top-n-grams and latent semantic ana
Background: Protein remote homology detection and fold recognition are central problems in bioinformatics. Currently, discriminative methods based on support vector machine (SVM) ...
Bin Liu, Xiaolong Wang, Lei Lin, Qiwen Dong, Xuan ...
BMCBI
2004
93views more  BMCBI 2004»
15 years 3 months ago
Predicting binding sites of hydrolase-inhibitor complexes by combining several methods
Background: Protein-protein interactions play a critical role in protein function. Completion of many genomes is being followed rapidly by major efforts to identify interacting pr...
Taner Z. Sen, Andrzej Kloczkowski, Robert L. Jerni...
BIOINFORMATICS
2011
14 years 6 months ago
A method for probing the mutational landscape of amyloid structure
Motivation: Proteins of all kinds can self-assemble into highly ordered β-sheet aggregates known as amyloid fibrils, important both biologically and clinically. However, the spe...
Charles W. O'Donnell, Jérôme Waldisp&...