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BMCBI
2010
111views more  BMCBI 2010»
15 years 3 months ago
Protein sequences classification by means of feature extraction with substitution matrices
Background: This paper deals with the preprocessing of protein sequences for supervised classification. Motif extraction is one way to address that task. It has been largely used ...
Rabie Saidi, Mondher Maddouri, Engelbert Mephu Ngu...
BIOINFORMATICS
2006
129views more  BIOINFORMATICS 2006»
15 years 3 months ago
Predicting methylation status of CpG islands in the human brain
Motivation: Over 50% of human genes contain CpG islands in their 5'-regions. Methylation patterns of CpG islands are involved in tissue-specific gene expression and regulatio...
Fang Fang, Shicai Fan, Xuegong Zhang, Michael Q. Z...
BIOINFORMATICS
2004
99views more  BIOINFORMATICS 2004»
15 years 3 months ago
EST clustering error evaluation and correction
Motivation: The gene expression intensity information conveyed by (EST) Expressed Sequence Tag data can be used to infer important cDNA library properties, such as gene number and...
Ji-Ping Z. Wang, Bruce G. Lindsay 0002, James Leeb...
BIOINFORMATICS
2002
146views more  BIOINFORMATICS 2002»
15 years 3 months ago
A duplication growth model of gene expression networks
Motivation: There has been considerable interest in developing computational techniques for inferring genetic regulatory networks from whole-genome expression profiles. When expre...
Ashish Bhan, David J. Galas, T. Gregory Dewey
KDD
2006
ACM
149views Data Mining» more  KDD 2006»
16 years 3 months ago
Regularized discriminant analysis for high dimensional, low sample size data
Linear and Quadratic Discriminant Analysis have been used widely in many areas of data mining, machine learning, and bioinformatics. Friedman proposed a compromise between Linear ...
Jieping Ye, Tie Wang