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RECOMB
2003
Springer
15 years 10 months ago
Modeling dependencies in protein-DNA binding sites
The availability of whole genome sequences and high-throughput genomic assays opens the door for in silico analysis of transcription regulation. This includes methods for discover...
Yoseph Barash, Gal Elidan, Nir Friedman, Tommy Kap...
ICDM
2006
IEEE
122views Data Mining» more  ICDM 2006»
15 years 3 months ago
Optimal Segmentation Using Tree Models
Sequence data are abundant in application areas such as computational biology, environmental sciences, and telecommunications. Many real-life sequences have a strong segmental str...
Robert Gwadera, Aristides Gionis, Heikki Mannila
NIPS
2001
14 years 11 months ago
Linear-time inference in Hierarchical HMMs
The hierarchical hidden Markov model (HHMM) is a generalization of the hidden Markov model (HMM) that models sequences with structure at many length/time scales [FST98]. Unfortuna...
K. P. Murphy, Mark A. Paskin
BMCBI
2006
92views more  BMCBI 2006»
14 years 10 months ago
A jumping profile Hidden Markov Model and applications to recombination sites in HIV and HCV genomes
Background: Jumping alignments have recently been proposed as a strategy to search a given multiple sequence alignment A against a database. Instead of comparing a database sequen...
Anne-Kathrin Schultz, Ming Zhang, Thomas Leitner, ...
JCSS
2007
116views more  JCSS 2007»
14 years 9 months ago
The most probable annotation problem in HMMs and its application to bioinformatics
Hidden Markov models (HMMs) are often used for biological sequence annotation. Each sequence feature is represented by a collection of states with the same label. In annotating a ...
Brona Brejová, Daniel G. Brown 0001, Tom&aa...