401 search results - page 4 / 81 » Generalizations of Markov model to characterize biological s... |
ISMB
1998
14 years 11 months ago
1998
A novel method to model and predict the location and orientation of alpha helices in membrane- spanning proteins is presented. It is based on a hidden Markov model (HMM) with an a...
BMCBI
2010
14 years 10 months ago
2010
Background: The Medium-chain Dehydrogenases/Reductases (MDR) form a protein superfamily whose size and complexity defeats traditional means of subclassification; it currently has ...
CANDC
2000
ACM
14 years 9 months ago
2000
ACM
A new statistical model for DNA considers a sequence to be a mixture of regions with little structure and regions that are approximate repeats of other subsequences, i.e. instance...
ISMB
1996
14 years 11 months ago
1996
Multiple sequence alignment of distantly related viral proteins remains a challenge to all currently available alignment methods. The hidden Markovmodel approach offers a new,flex...
RECOMB
2001
Springer
15 years 10 months ago
2001
Springer
We present a novel distance-based algorithm for evolutionary tree reconstruction. Our algorithm reconstructs the topology of a tree with n leaves in O(n2 ) time using O(n) working...