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BMCBI
2006
137views more  BMCBI 2006»
14 years 10 months ago
A maximum likelihood framework for protein design
Background: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, thi...
Claudia L. Kleinman, Nicolas Rodrigue, Céci...
LMCS
2006
98views more  LMCS 2006»
14 years 9 months ago
Approximate reasoning for real-time probabilistic processes
We develop a pseudo-metric analogue of bisimulation for generalized semi-Markov processes. The kernel of this pseudo-metric corresponds to bisimulation; thus we have extended bisi...
Vineet Gupta, Radha Jagadeesan, Prakash Panangaden
BMCBI
2007
125views more  BMCBI 2007»
14 years 10 months ago
Statistical tests to compare motif count exceptionalities
Background: Finding over- or under-represented motifs in biological sequences is now a common task in genomics. Thanks to p-value calculation for motif counts, exceptional motifs ...
Stéphane Robin, Sophie Schbath, Vincent Van...
INFOCOM
2003
IEEE
15 years 3 months ago
Asymptotic Insensitivity of Least-Recently-Used Caching to Statistical Dependency
Abstract— We investigate a widely popular Least-RecentlyUsed (LRU) cache replacement algorithm with semi-Markov modulated requests. Semi-Markov processes provide the flexibility...
Predrag R. Jelenkovic, Ana Radovanovic
BMCBI
2008
111views more  BMCBI 2008»
14 years 10 months ago
GENOMEPOP: A program to simulate genomes in populations
Background: There are several situations in population biology research where simulating DNA sequences is useful. Simulation of biological populations under different evolutionary...
Antonio Carvajal-Rodríguez