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BMCBI
2005
100views more  BMCBI 2005»
14 years 9 months ago
Evolutionary models for insertions and deletions in a probabilistic modeling framework
Background: Probabilistic models for sequence comparison (such as hidden Markov models and pair hidden Markov models for proteins and mRNAs, or their context-free grammar counterp...
Elena Rivas
BMCBI
2008
128views more  BMCBI 2008»
14 years 10 months ago
Finding sequence motifs with Bayesian models incorporating positional information: an application to transcription factor bindin
Background: Biologically active sequence motifs often have positional preferences with respect to a genomic landmark. For example, many known transcription factor binding sites (T...
Nak-Kyeong Kim, Kannan Tharakaraman, Leonardo Mari...
ISAMI
2010
14 years 7 months ago
Employing Compact Intra-genomic Language Models to Predict Genomic Sequences and Characterize Their Entropy
Probabilistic models of languages are fundamental to understand and learn the profile of the subjacent code in order to estimate its entropy, enabling the verification and predicti...
Sérgio A. D. Deusdado, Paulo Carvalho
ISMB
1997
14 years 11 months ago
Identifying Chimerism in Proteins Using Hidden Markov Models of Codon Usage
Protein chimerism is a phenomenon involving the combination of multiple ancestral sequences into a single, multi-domain protein through evolution. We propose a novel method for de...
Lawrence Hunter, Barry Zeeberg
SPIRE
2009
Springer
15 years 2 months ago
Faster Algorithms for Sampling and Counting Biological Sequences
Abstract. A set of sequences S is pairwise bounded if the Hamming distance between any pair of sequences in S is at most 2d. The Consensus Sequence problem aims to discern between ...
Christina Boucher