Background: Reverse engineering cellular networks is currently one of the most challenging problems in systems biology. Dynamic Bayesian networks (DBNs) seem to be particularly su...
Fulvia Ferrazzi, Paola Sebastiani, Marco Ramoni, R...
In biological applications, the tandem mass spectrometry is a widely used method for determining protein and peptide sequences from an ”in vitro” sample. The sequences are not...
We have continued to develop MITOMAP (http://www.gen.emory.edu/MITOMAP ), a comprehensive database for the human mitochondrial DNA (mtDNA). MITOMAP uses the mtDNA sequence as the ...
Andreas M. Kogelnik, Marie T. Lott, Michael D. Bro...
A major bottleneck in high-throughput protein crystallography is producing protein-structure models from an electrondensity map. In previous work, we developed Acmi, a probabilist...
Background: When accurate models for the divergent evolution of protein sequences are integrated with complementary biological information, such as folded protein structures, anal...