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BMCBI
2008
93views more  BMCBI 2008»
14 years 11 months ago
MPDA: Microarray pooled DNA analyzer
Background: Microarray-based pooled DNA experiments that combine the merits of DNA pooling and gene chip technology constitute a pivotal advance in biotechnology. This new techniq...
Hsin-Chou Yang, Mei-Chu Huang, Ling-Hui Li, Chien-...
BMCBI
2008
107views more  BMCBI 2008»
14 years 11 months ago
Multi-agent systems in epidemiology: a first step for computational biology in the study of vector-borne disease transmission
Background: Computational biology is often associated with genetic or genomic studies only. However, thanks to the increase of computational resources, computational models are ap...
Benjamin Roche, Jean-François Guégan...
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BMCBI
2008
118views more  BMCBI 2008»
14 years 11 months ago
Evaluation of phylogenetic footprint discovery for predicting bacterial cis-regulatory elements and revealing their evolution
Background: The detection of conserved motifs in promoters of orthologous genes (phylogenetic footprints) has become a common strategy to predict cis-acting regulatory elements. S...
Rekin's Janky, Jacques van Helden
BMCBI
2007
145views more  BMCBI 2007»
14 years 11 months ago
Genome bioinformatic analysis of nonsynonymous SNPs
Background: Genome-wide association studies of common diseases for common, low penetrance causal variants are underway. A proportion of these will alter protein sequences, the mos...
David F. Burke, Catherine L. Worth, Eva-Maria Prie...
BMCBI
2008
171views more  BMCBI 2008»
14 years 11 months ago
Comparative analysis of five protein-protein interaction corpora
Background: Growing interest in the application of natural language processing methods to biomedical text has led to an increasing number of corpora and methods targeting protein-...
Sampo Pyysalo, Antti Airola, Juho Heimonen, Jari B...