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BMCBI
2007
134views more  BMCBI 2007»
15 years 4 months ago
Automatic generation of 3D motifs for classification of protein binding sites
Background: Since many of the new protein structures delivered by high-throughput processes do not have any known function, there is a need for structure-based prediction of prote...
Jean-Christophe Nebel, Pawel Herzyk, David R. Gilb...
BMCBI
2008
133views more  BMCBI 2008»
15 years 4 months ago
MS-DOCK: Accurate multiple conformation generator and rigid docking protocol for multi-step virtual ligand screening
Background: The number of protein targets with a known or predicted tri-dimensional structure and of drug-like chemical compounds is growing rapidly and so is the need for new the...
Nicolas Sauton, David Lagorce, Bruno O. Villoutrei...
BMCBI
2008
118views more  BMCBI 2008»
15 years 4 months ago
Drug interaction prediction using ontology-driven hypothetical assertion framework for pathway generation followed by numerical
Background: In accordance with the increasing amount of information concerning individual differences in drug response and molecular interaction, the role of in silico prediction ...
Takeshi Arikuma, Sumi Yoshikawa, Ryuzo Azuma, Kent...
BMCBI
2007
96views more  BMCBI 2007»
15 years 4 months ago
Features generated for computational splice-site prediction correspond to functional elements
Background: Accurate selection of splice sites during the splicing of precursors to messenger RNA requires both relatively well-characterized signals at the splice sites and auxil...
Rezarta Islamaj Dogan, Lise Getoor, W. John Wilbur...
IJFCS
2008
102views more  IJFCS 2008»
15 years 4 months ago
Succinct Minimal Generators: Theoretical Foundations and Applications
In data mining applications, highly sized contexts are handled what usually results in a considerably large set of frequent itemsets, even for high values of the minimum support t...
Tarek Hamrouni, Sadok Ben Yahia, Engelbert Mephu N...