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BMCBI
2010
108views more  BMCBI 2010»
15 years 3 months ago
Comparison of scores for bimodality of gene expression distributions and genome-wide evaluation of the prognostic relevance of h
Background: A major goal of the analysis of high-dimensional RNA expression data from tumor tissue is to identify prognostic signatures for discriminating patient subgroups. For t...
Birte Hellwig, Jan G. Hengstler, Marcus Schmidt, M...
BMCBI
2010
117views more  BMCBI 2010»
15 years 3 months ago
Extracting causal relations on HIV drug resistance from literature
Background: In HIV treatment it is critical to have up-to-date resistance data of applicable drugs since HIV has a very high rate of mutation. These data are made available throug...
Quoc-Chinh Bui, Breanndán Ó Nuall&aa...
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BMCBI
2010
130views more  BMCBI 2010»
15 years 3 months ago
The behaviour of random forest permutation-based variable importance measures under predictor correlation
Background: Random forests (RF) have been increasingly used in applications such as genome-wide association and microarray studies where predictor correlation is frequently observ...
Kristin K. Nicodemus, James D. Malley, Carolin Str...
BMCBI
2010
110views more  BMCBI 2010»
15 years 3 months ago
Missing value imputation for epistatic MAPs
Background: Epistatic miniarray profiling (E-MAPs) is a high-throughput approach capable of quantifying aggravating or alleviating genetic interactions between gene pairs. The dat...
Colm Ryan, Derek Greene, Gerard Cagney, Padraig Cu...
BIOINFORMATICS
2007
137views more  BIOINFORMATICS 2007»
15 years 3 months ago
Annotation-based distance measures for patient subgroup discovery in clinical microarray studies
: Background Clustering algorithms are widely used in the analysis of microarray data. In clinical studies, they are often applied to find groups of co-regulated genes. Clustering...
Claudio Lottaz, Joern Toedling, Rainer Spang
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