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BMCBI
2010
77views more  BMCBI 2010»
15 years 3 months ago
web cellHTS2: A web-application for the analysis of high-throughput screening data
Background: The analysis of high-throughput screening data sets is an expanding field in bioinformatics. Highthroughput screens by RNAi generate large primary data sets which need...
Oliver Pelz, Moritz Gilsdorf, Michael Boutros
BMCBI
2010
188views more  BMCBI 2010»
15 years 3 months ago
CDK-Taverna: an open workflow environment for cheminformatics
Background: Small molecules are of increasing interest for bioinformatics in areas such as metabolomics and drug discovery. The recent release of large open access chemistry datab...
Thomas Kuhn, Egon L. Willighagen, Achim Zielesny, ...
BMCBI
2010
156views more  BMCBI 2010»
15 years 3 months ago
Evaluation of statistical methods for normalization and differential expression in mRNA-Seq experiments
Background: High-throughput sequencing technologies, such as the Illumina Genome Analyzer, are powerful new tools for investigating a wide range of biological and medical question...
James H. Bullard, Elizabeth Purdom, Kasper D. Hans...
BMCBI
2010
109views more  BMCBI 2010»
15 years 3 months ago
Predicting gene function using hierarchical multi-label decision tree ensembles
Background: S. cerevisiae, A. thaliana and M. musculus are well-studied organisms in biology and the sequencing of their genomes was completed many years ago. It is still a challe...
Leander Schietgat, Celine Vens, Jan Struyf, Hendri...
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BMCBI
2010
176views more  BMCBI 2010»
15 years 3 months ago
TargetSpy: a supervised machine learning approach for microRNA target prediction
Background: Virtually all currently available microRNA target site prediction algorithms require the presence of a (conserved) seed match to the 5' end of the microRNA. Recen...
Martin Sturm, Michael Hackenberg, David Langenberg...
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