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BMCBI
2010
15 years 3 months ago
2010
Background: Thermophilic proteins sustain themselves and function at higher temperatures. Despite their structural and functional similarities with their mesophilic homologues, th...
123
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BMCBI
2007
15 years 3 months ago
2007
Background: Data clustering analysis has been extensively applied to extract information from gene expression profiles obtained with DNA microarrays. To this aim, existing cluster...
129
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BMCBI
2007
15 years 3 months ago
2007
Background: When conducting multiple hypothesis tests, it is important to control the number of false positives, or the False Discovery Rate (FDR). However, there is a tradeoff be...
142
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BMCBI
2008
15 years 3 months ago
2008
Background: The increasing amount of published literature in biomedicine represents an immense source of knowledge, which can only efficiently be accessed by a new generation of a...
109
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BMCBI
2010
15 years 3 months ago
2010
Background: Protein conformation and protein/protein interaction can be elucidated by solution-phase Hydrogen/ Deuterium exchange (sHDX) coupled to high-resolution mass analysis o...