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BMCBI
2005
134views more  BMCBI 2005»
14 years 11 months ago
Ancestral sequence alignment under optimal conditions
Background: Multiple genome alignment is an important problem in bioinformatics. An important subproblem used by many multiple alignment approaches is that of aligning two multipl...
Alexander K. Hudek, Daniel G. Brown 0001
BMCBI
2005
163views more  BMCBI 2005»
14 years 11 months ago
Rank-invariant resampling based estimation of false discovery rate for analysis of small sample microarray data
Background: The evaluation of statistical significance has become a critical process in identifying differentially expressed genes in microarray studies. Classical p-value adjustm...
Nitin Jain, HyungJun Cho, Michael O'Connell, Jae K...
BMCBI
2005
73views more  BMCBI 2005»
14 years 11 months ago
An analysis of extensible modelling for functional genomics data
Background: Several data formats have been developed for large scale biological experiments, using a variety of methodologies. Most data formats contain a mechanism for allowing e...
Andrew R. Jones, Norman W. Paton
BMCBI
2005
84views more  BMCBI 2005»
14 years 11 months ago
A note on generalized Genome Scan Meta-Analysis statistics
Background: Wise et al. introduced a rank-based statistical technique for meta-analysis of genome scans, the Genome Scan Meta-Analysis (GSMA) method. Levinson et al. recently desc...
James A. Koziol, Anne C. Feng
BMCBI
2005
97views more  BMCBI 2005»
14 years 11 months ago
Clustering the annotation space of proteins
Background: Current protein clustering methods rely on either sequence or functional similarities between proteins, thereby limiting inferences to one of these areas. Results: Her...
Victor Kunin, Christos A. Ouzounis
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