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BMCBI
2005
106views more  BMCBI 2005»
14 years 11 months ago
SIMPROT: Using an empirically determined indel distribution in simulations of protein evolution
Background: General protein evolution models help determine the baseline expectations for the evolution of sequences, and they have been extensively useful in sequence analysis an...
Andy Pang, Andrew D. Smith, Paulo A. S. Nuin, Elis...
BMCBI
2005
79views more  BMCBI 2005»
14 years 11 months ago
Mathematical design of prokaryotic clone-based microarrays
Background: Clone-based microarrays, on which each spot represents a random genomic fragment, are a good alternative to open reading frame-based microarrays, especially for microo...
Bart Pieterse, Elisabeth J. Quirijns, Frank H. J. ...
BMCBI
2005
100views more  BMCBI 2005»
14 years 11 months ago
Evolutionary models for insertions and deletions in a probabilistic modeling framework
Background: Probabilistic models for sequence comparison (such as hidden Markov models and pair hidden Markov models for proteins and mRNAs, or their context-free grammar counterp...
Elena Rivas
TJS
2008
105views more  TJS 2008»
14 years 11 months ago
Using a relational database for scalable XML search
XML is a flexible and powerful tool that enables information and security sharing in heterogeneous environments. Scalable technologies are needed to effectively manage the growing...
Rebecca Cathey, Steven M. Beitzel, Eric C. Jensen,...
BMCBI
2005
141views more  BMCBI 2005»
14 years 11 months ago
A method for the prediction of GPCRs coupling specificity to G-proteins using refined profile Hidden Markov Models
Background: G- Protein coupled receptors (GPCRs) comprise the largest group of eukaryotic cell surface receptors with great pharmacological interest. A broad range of native ligan...
Nikolaos G. Sgourakis, Pantelis G. Bagos, Panagiot...
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