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» Generating Ambiguity in the Laboratory
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BMCBI
2006
88views more  BMCBI 2006»
14 years 9 months ago
RiboSubstrates: a web application addressing the cleavage specificities of ribozymes in designated genomes
Background: RNA-dependent gene silencing is becoming a routine tool used in laboratories worldwide. One of the important remaining hurdles in the selection of the target sequence,...
Jean-François Lucier, Lucien Junior Bergero...
BMCBI
2007
105views more  BMCBI 2007»
14 years 9 months ago
Extended analysis of benchmark datasets for Agilent two-color microarrays
Background: As part of its broad and ambitious mission, the MicroArray Quality Control (MAQC) project reported the results of experiments using External RNA Controls (ERCs) on fiv...
Kathleen F. Kerr
BMCBI
2007
144views more  BMCBI 2007»
14 years 9 months ago
Automatic delineation of malignancy in histopathological head and neck slides
Background: Histopathology, which is one of the most important routines of all laboratory procedures used in pathology, is decisive for the diagnosis of cancer. Experienced histop...
Mutlu Mete, Xiaowei Xu, Chun-Yang Fan, Gal Shafirs...
FGCS
2006
144views more  FGCS 2006»
14 years 9 months ago
BioSimGrid: Grid-enabled biomolecular simulation data storage and analysis
In computational biomolecular research, large amounts of simulation data are generated to capture the motion of proteins. These massive simulation data can be analysed in a number...
Muan Hong Ng, Steven Johnston, Bing Wu, Stuart E. ...
JCB
2008
91views more  JCB 2008»
14 years 9 months ago
Computational Quantification of Peptides from LC-MS Data
Liquid chromatography coupled to mass spectrometry (LC-MS) has become a major tool for the study of biological processes. High-throughput LC-MS experiments are frequently conducte...
Ole Schulz-Trieglaff, Rene Hussong, Clemens Gr&oum...