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BMCBI
2008
92views more  BMCBI 2008»
14 years 10 months ago
A semiparametric modeling framework for potential biomarker discovery and the development of metabonomic profiles
Background: The discovery of biomarkers is an important step towards the development of criteria for early diagnosis of disease status. Recently electrospray ionization (ESI) and ...
Samiran Ghosh, David F. Grant, Dipak K. Dey, Denni...
TSE
2010
136views more  TSE 2010»
14 years 8 months ago
A Theoretical and Empirical Study of Search-Based Testing: Local, Global, and Hybrid Search
Search based optimization techniques have been applied to structural software test data generation since 1992, with a recent upsurge in interest and activity within this area. How...
Mark Harman, Phil McMinn
BMCBI
2004
112views more  BMCBI 2004»
14 years 10 months ago
MuTrack: a genome analysis system for large-scale mutagenesis in the mouse
Background: Modern biological research makes possible the comprehensive study and development of heritable mutations in the mouse model at high-throughput. Using techniques spanni...
Erich J. Baker, Leslie Galloway, Barbara Jackson, ...
ICML
2007
IEEE
15 years 10 months ago
Non-isometric manifold learning: analysis and an algorithm
In this work we take a novel view of nonlinear manifold learning. Usually, manifold learning is formulated in terms of finding an embedding or `unrolling' of a manifold into ...
Piotr Dollár, Serge J. Belongie, Vincent Ra...
BMCBI
2008
152views more  BMCBI 2008»
14 years 10 months ago
Predicting biological system objectives de novo from internal state measurements
Background: Optimization theory has been applied to complex biological systems to interrogate network properties and develop and refine metabolic engineering strategies. For examp...
Erwin P. Gianchandani, Matthew A. Oberhardt, Antho...