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GECCO
2008
Springer
154views Optimization» more  GECCO 2008»
15 years 5 months ago
Automated shape composition based on cell biology and distributed genetic programming
Motivated by the ability of living cells to form specific shapes and structures, we present a computational approach using distributed genetic programming to discover cell-cell i...
Linge Bai, Manolya Eyiyurekli, David E. Breen
GECCO
2010
Springer
244views Optimization» more  GECCO 2010»
15 years 4 months ago
Implicit fitness and heterogeneous preferences in the genetic algorithm
This paper takes an economic approach to derive an evolutionary learning model based entirely on the endogenous employment of genetic operators in the service of self-interested a...
Justin T. H. Smith
BMCBI
2008
84views more  BMCBI 2008»
15 years 4 months ago
poolHiTS: A Shifted Transversal Design based pooling strategy for high-throughput drug screening
Background: A key goal of drug discovery is to increase the throughput of small molecule screens without sacrificing screening accuracy. High-throughput screening (HTS) in drug di...
Raghunandan M. Kainkaryam, Peter J. Woolf
BMCBI
2010
190views more  BMCBI 2010»
15 years 4 months ago
Sample size and statistical power considerations in high-dimensionality data settings: a comparative study of classification alg
Background: Data generated using `omics' technologies are characterized by high dimensionality, where the number of features measured per subject vastly exceeds the number of...
Yu Guo, Armin Graber, Robert N. McBurney, Raji Bal...
BMCBI
2008
104views more  BMCBI 2008»
15 years 4 months ago
Evolutionary Pareto-optimization of stably folding peptides
Background: As a rule, peptides are more flexible and unstructured than proteins with their substantial stabilizing hydrophobic cores. Nevertheless, a few stably folding peptides ...
Wolfram Gronwald, Tim Hohm, Daniel Hoffmann
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