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BMCBI
2007
136views more  BMCBI 2007»
15 years 2 months ago
Reduced modeling of signal transduction - a modular approach
Background: Combinatorial complexity is a challenging problem in detailed and mechanistic mathematical modeling of signal transduction. This subject has been discussed intensively...
Markus Koschorreck, Holger Conzelmann, Sybille Ebe...
BMCBI
2007
146views more  BMCBI 2007»
15 years 2 months ago
Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data
Background: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental ...
Xiangdong Liu, Walter J. Jessen, Siva Sivaganesan,...
BMCBI
2007
130views more  BMCBI 2007»
15 years 2 months ago
Reproducibility of microarray data: a further analysis of microarray quality control (MAQC) data
Background: Many researchers are concerned with the comparability and reliability of microarray gene expression data. Recent completion of the MicroArray Quality Control (MAQC) pr...
James J. Chen, Huey-miin Hsueh, Robert R. Delongch...
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BMCBI
2008
175views more  BMCBI 2008»
15 years 2 months ago
Synonym set extraction from the biomedical literature by lexical pattern discovery
Background: Although there are a large number of thesauri for the biomedical domain many of them lack coverage in terms and their variant forms. Automatic thesaurus construction b...
John McCrae, Nigel Collier
BMCBI
2008
104views more  BMCBI 2008»
15 years 2 months ago
ReRep: Computational detection of repetitive sequences in genome survey sequences (GSS)
Background: Genome survey sequences (GSS) offer a preliminary global view of a genome since, unlike ESTs, they cover coding as well as non-coding DNA and include repetitive region...
Thomas D. Otto, Leonardo H. F. Gomes, Marcelo Alve...
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