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» Genetic Algorithms for Component Analysis
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132
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GECCO
2007
Springer
177views Optimization» more  GECCO 2007»
15 years 9 months ago
Takeover times on scale-free topologies
The topological properties of a network directly impact the flow of information through a system. In evolving populations, the topology of inter-individual interactions affects th...
Joshua L. Payne, Margaret J. Eppstein
131
Voted
BMCBI
2010
117views more  BMCBI 2010»
15 years 3 months ago
Automatic, context-specific generation of Gene Ontology slims
Background: The use of ontologies to control vocabulary and structure annotation has added value to genomescale data, and contributed to the capture and re-use of knowledge across...
Melissa J. Davis, Muhammad Shoaib B. Sehgal, Mark ...
152
Voted
BMCBI
2007
161views more  BMCBI 2007»
15 years 3 months ago
Efficient classification of complete parameter regions based on semidefinite programming
Background: Current approaches to parameter estimation are often inappropriate or inconvenient for the modelling of complex biological systems. For systems described by nonlinear ...
Lars Kuepfer, Uwe Sauer, Pablo A. Parrilo
BMCBI
2007
111views more  BMCBI 2007»
15 years 3 months ago
MotifCombinator: a web-based tool to search for combinations of cis-regulatory motifs
Background: A combination of multiple types of transcription factors and cis-regulatory elements is often required for gene expression in eukaryotes, and the combinatorial regulat...
Mamoru Kato, Tatsuhiko Tsunoda
133
Voted
JAMIA
2011
98views more  JAMIA 2011»
14 years 6 months ago
Mapping clinical phenotype data elements to standardized metadata repositories and controlled terminologies: the eMERGE Network
Background Systematic study of clinical phenotypes is important for a better understanding of the genetic basis of human diseases and more effective gene-based disease management....
Jyotishman Pathak, Janey Wang, Sudha Kashyap, Meli...