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» Genetic Algorithms for Protein Threading
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RECOMB
2003
Springer
15 years 10 months ago
Modeling dependencies in protein-DNA binding sites
The availability of whole genome sequences and high-throughput genomic assays opens the door for in silico analysis of transcription regulation. This includes methods for discover...
Yoseph Barash, Gal Elidan, Nir Friedman, Tommy Kap...
BMCBI
2008
102views more  BMCBI 2008»
14 years 9 months ago
Improving protein function prediction methods with integrated literature data
Background: Determining the function of uncharacterized proteins is a major challenge in the post-genomic era due to the problem's complexity and scale. Identifying a protein...
Aaron Gabow, Sonia M. Leach, William A. Baumgartne...
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EVOW
2004
Springer
15 years 3 months ago
Two-Step Genetic Programming for Optimization of RNA Common-Structure
We present an algorithm for identifying putative non-coding RNA (ncRNA) using an RCSG (RNA Common-Structural Grammar) and show the effectiveness of the algorithm. The algorithm con...
Jin-Wu Nam, Je-Gun Joung, Y. S. Ahn, Byoung-Tak Zh...
CEC
2005
IEEE
15 years 3 months ago
Evolving hidden Markov models for protein secondary structure prediction
New results are presented for the prediction of secondary structure information for protein sequences using Hidden Markov Models (HMMs) evolved using a Genetic Algorithm (GA). We a...
Kyoung-Jae Won, Thomas Hamelryck, Adam Prügel...
BMCBI
2006
117views more  BMCBI 2006»
14 years 9 months ago
Gene Designer: a synthetic biology tool for constructing artificial DNA segments
Background: Direct synthesis of genes is rapidly becoming the most efficient way to make functional genetic constructs and enables applications such as codon optimization, RNAi re...
Alan Villalobos, Jon E. Ness, Claes Gustafsson, Je...