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BMCBI
2008
121views more  BMCBI 2008»
15 years 5 months ago
Microarray data mining using landmark gene-guided clustering
Background: Clustering is a popular data exploration technique widely used in microarray data analysis. Most conventional clustering algorithms, however, generate only one set of ...
Pankaj Chopra, Jaewoo Kang, Jiong Yang, HyungJun C...
164
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GECCO
2010
Springer
191views Optimization» more  GECCO 2010»
15 years 9 months ago
Initialization parameter sweep in ATHENA: optimizing neural networks for detecting gene-gene interactions in the presence of sma
Recent advances in genotyping technology have led to the generation of an enormous quantity of genetic data. Traditional methods of statistical analysis have proved insufficient i...
Emily Rose Holzinger, Carrie C. Buchanan, Scott M....
157
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BMCBI
2006
117views more  BMCBI 2006»
15 years 5 months ago
Gene Designer: a synthetic biology tool for constructing artificial DNA segments
Background: Direct synthesis of genes is rapidly becoming the most efficient way to make functional genetic constructs and enables applications such as codon optimization, RNAi re...
Alan Villalobos, Jon E. Ness, Claes Gustafsson, Je...
JCB
2006
114views more  JCB 2006»
15 years 4 months ago
A General Modeling Strategy for Gene Regulatory Networks with Stochastic Dynamics
A stochastic genetic toggle switch model that consists of two identical, mutually repressive genes is built using the Gillespie algorithm with time delays as an example of a simpl...
Andre Ribeiro, Rui Zhu, Stuart A. Kauffman
MAM
2007
157views more  MAM 2007»
15 years 4 months ago
Executing large algorithms on low-capacity FPGAs using flowpath partitioning and runtime reconfiguration
This paper describes a new method of executing a software program on an FPGA for embedded systems. Rather than combine reconfigurable logic with a microprocessor core, this method...
Darrin M. Hanna, Michael DuChene