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ICGA
1997
122views Optimization» more  ICGA 1997»
15 years 4 months ago
A Comparison of Global and Local Search Methods in Drug Docking
Molecular docking software makes computational predictions of the interaction of molecules. This can be useful, for example, in evaluating the binding of candidate drug molecules ...
Christopher D. Rosin, R. Scott Halliday, William E...
EVOW
2009
Springer
15 years 10 months ago
Evolutionary Optimization Guided by Entropy-Based Discretization
The Learnable Evolution Model (LEM) involves alternating periods of optimization and learning, performa extremely well on a range of problems, a specialises in achieveing good resu...
Guleng Sheri, David W. Corne
BMCBI
2006
175views more  BMCBI 2006»
15 years 3 months ago
Parameter estimation for stiff equations of biosystems using radial basis function networks
Background: The modeling of dynamic systems requires estimating kinetic parameters from experimentally measured time-courses. Conventional global optimization methods used for par...
Yoshiya Matsubara, Shinichi Kikuchi, Masahiro Sugi...
156
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ASIAN
2004
Springer
153views Algorithms» more  ASIAN 2004»
15 years 7 months ago
Chi-Square Matrix: An Approach for Building-Block Identification
This paper presents a line of research in genetic algorithms (GAs), called building-block identification. The building blocks (BBs) are common structures inferred from a set of sol...
Chatchawit Aporntewan, Prabhas Chongstitvatana
EVOW
2010
Springer
15 years 9 months ago
Investigating the Local-Meta-Model CMA-ES for Large Population Sizes
For many real-life engineering optimization problems, the cost of one objective function evaluation can take several minutes or hours. In this context, a popular approach to reduce...
Zyed Bouzarkouna, Anne Auger, Didier Yu Ding