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BMCBI
2008
99views more  BMCBI 2008»
14 years 9 months ago
Multiple organism algorithm for finding ultraconserved elements
Background: Ultraconserved elements are nucleotide or protein sequences with 100% identity (no mismatches, insertions, or deletions) in the same organism or between two or more or...
Scott Christley, Neil F. Lobo, Gregory R. Madey
BMCBI
2008
149views more  BMCBI 2008»
14 years 9 months ago
Evolution of biological sequences implies an extreme value distribution of type I for both global and local pairwise alignment s
Background: Confidence in pairwise alignments of biological sequences, obtained by various methods such as Blast or Smith-Waterman, is critical for automatic analyses of genomic d...
Olivier Bastien, Eric Maréchal
BMCBI
2004
136views more  BMCBI 2004»
14 years 9 months ago
A SNP-centric database for the investigation of the human genome
Background: Single Nucleotide Polymorphisms (SNPs) are an increasingly important tool for genetic and biomedical research. Although current genomic databases contain information o...
Alberto Riva, Isaac S. Kohane
SSDBM
2010
IEEE
220views Database» more  SSDBM 2010»
15 years 1 months ago
Prefix Tree Indexing for Similarity Search and Similarity Joins on Genomic Data
Similarity search and similarity join on strings are important for applications such as duplicate detection, error detection, data cleansing, or comparison of biological sequences....
Astrid Rheinländer, Martin Knobloch, Nicky Ho...
BMCBI
2006
98views more  BMCBI 2006»
14 years 9 months ago
The Secrets of a Functional Synapse - From a Computational and Experimental Viewpoint
Background: Neuronal communication is tightly regulated in time and in space. The neuronal transmission takes place in the nerve terminal, at a specialized structure called the sy...
Michal Linial