The Smith-Waterman algorithm for local sequence alignment is one of the most important techniques in computational molecular biology. This ingenious dynamic programming approach w...
Abstract. We describe a probabilistic model, implemented as a dynamic Bayesian network, that can be used to predict nucleosome positioning along a chromosome based on one or more g...
Sheila M. Reynolds, Zhiping Weng, Jeff A. Bilmes, ...
Abstract. Recent studies demonstrating the existence of special non-coding "antisense" RNAs used in post-transcriptional gene regulation have received considerable attent...
Abstract-- The DNA microarray technology, originally developed to measure the level of gene expression, had become one of the most widely used tools in genomic study. Microarrays h...
Leszek Gasieniec, Cindy Y. Li, Paul Sant, Prudence...
Background: Clustering the information content of large high-dimensional gene expression datasets has widespread application in "omics" biology. Unfortunately, the under...