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» Genome Sequence Assembly: Algorithms and Issues
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CSB
2002
IEEE
121views Bioinformatics» more  CSB 2002»
15 years 10 months ago
Fast and Sensitive Algorithm for Aligning ESTs to Human Genome
There is a pressing need to align growing set of expressed sequence tags (ESTs) to newly sequenced human genome. The problem is, however, complicated by the exon/intron structure ...
Jun Ogasawara, Shinichi Morishita
FPL
2010
Springer
188views Hardware» more  FPL 2010»
15 years 3 months ago
SeqHive: A Reconfigurable Computer Cluster for Genome Re-sequencing
We demonstrate how Field Programmable Gate Arrays (FPGAs) may be used to address the computing challenges associated with assembling genome sequences from recent ultra-high-through...
Kristian Stevens, Henry Chen, Terry Filiba, Peter ...
ESA
2001
Springer
105views Algorithms» more  ESA 2001»
15 years 10 months ago
SNPs Problems, Complexity, and Algorithms
Abstract. Single nucleotide polymorphisms (SNPs) are the most frequent form of human genetic variation. They are of fundamental importance for a variety of applications including m...
Giuseppe Lancia, Vineet Bafna, Sorin Istrail, Ross...
APBC
2004
15 years 7 months ago
Mega Weaver: A Simple Iterative Approach for BAC Consensus Assembly
Hierarchical genome assembly can be divided into three distinct stages: sequencing and assembling shotgun reads for each of a series of selected BAC clones; assembling the resulti...
Daolong Wang, Mario Lauria, Bo Yuan, Fred A. Wrigh...
160
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BMCBI
2010
183views more  BMCBI 2010»
15 years 5 months ago
SOPRA: Scaffolding algorithm for paired reads via statistical optimization
Background: High throughput sequencing (HTS) platforms produce gigabases of short read (<100 bp) data per run. While these short reads are adequate for resequencing application...
Adel Dayarian, Todd P. Michael, Anirvan M. Sengupt...