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» Genome rearrangements with duplications
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RECOMB
2008
Springer
15 years 10 months ago
Estimating the Relative Contributions of New Genes from Retrotransposition and Segmental Duplication Events during Mammalian Evo
Gene duplication has long been recognized as a major force in genome evolution and has recently been recognized as an important source of individual variation. For many years the o...
Jin Jun, Paul Ryvkin, Edward Hemphill, Ion I. Mand...
RECOMB
2005
Springer
15 years 10 months ago
On Sorting by Translocations
The study of genome rearrangements is an important tool in comparative genomics. This paper revisits the problem of sorting a multichromosomal genome by translocations, i.e. exchan...
Anne Bergeron, Julia Mixtacki, Jens Stoye
RECOMB
2007
Springer
15 years 10 months ago
A Heuristic Algorithm for Reconstructing Ancestral Gene Orders with Duplications
Accurately reconstructing the large-scale gene order in an ancestral genome is a critical step to better understand genome evolution. In this paper, we propose a heuristic algorith...
Jian Ma, Aakrosh Ratan, Louxin Zhang, Webb Miller,...
TCBB
2010
137views more  TCBB 2010»
14 years 4 months ago
The Metropolized Partial Importance Sampling MCMC Mixes Slowly on Minimum Reversal Rearrangement Paths
Markov chain Monte Carlo has been the standard technique for inferring the posterior distribution of genome rearrangement scenarios under a Bayesian approach. We present here a neg...
István Miklós, Bence Melykuti, Krist...
WABI
2004
Springer
15 years 3 months ago
Chaining Algorithms for Alignment of Draft Sequence
Abstract. In this paper we propose a chaining method that can align a draft genomic sequence against a finished genome. We introduce the use of an overlap tree to enhance the state...
Mukund Sundararajan, Michael Brudno, Kerrin Small,...