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» Genome rearrangements with duplications
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BMCBI
2011
14 years 5 months ago
Screening synteny blocks in pairwise genome comparisons through integer programming
Background: It is difficult to accurately interpret chromosomal correspondences such as true orthology and paralogy due to significant divergence of genomes from a common ancestor...
Haibao Tang, Eric Lyons, Brent S. Pedersen, James ...
JDA
2008
122views more  JDA 2008»
14 years 9 months ago
An approximation algorithm for sorting by reversals and transpositions
Abstract. Genome rearrangement algorithms are powerful tools to analyze gene orders in molecular evolution. Analysis of genomes evolving by reversals and transpositions leads to a ...
Atif Rahman, Swakkhar Shatabda, Masud Hasan
BMCBI
2011
14 years 1 months ago
Detection of recurrent rearrangement breakpoints from copy number data
Background: Copy number variants (CNVs), including deletions, amplifications, and other rearrangements, are common in human and cancer genomes. Copy number data from array compara...
Anna M. Ritz, Pamela L. Paris, Michael Ittmann, Co...
NAR
2007
117views more  NAR 2007»
14 years 9 months ago
FGF: A web tool for Fishing Gene Family in a whole genome database
Gene duplication is an important process in evolution. The availability of genome sequences of a number of organisms has made it possible to conduct comprehensive searches for dup...
Hongkun Zheng, Junjie Shi, Xiaodong Fang, Yuan Li,...
NAR
2011
216views Computer Vision» more  NAR 2011»
14 years 25 days ago
dbDNV: a resource of duplicated gene nucleotide variants in human genome
Gene duplications are scattered widely throughout the human genome. A single-base difference located in nearly identical duplicated segments may be misjudged as a single nucleotid...
Meng-Ru Ho, Kuo-Wang Tsai, Chun-houh Chen, Wen-cha...