The problem of Sorting signed permutations by reversals is a well studied problem in computational biology. The first polynomial time algorithm was presented by Hannenhalli and Pev...
A transposition is an operation that exchanges two adjacent substrings. When it is restricted so that one of the substrings is a prefix, it is called a prefix transposition. The p...
Protein dispensability is fundamental to understanding of gene function and evolution. It is usually studied at the individual gene phenotype level. Recent advances in generating ...
Background: Both somatic copy number alterations (CNAs) and germline copy number variants (CNVs) that are prevalent in healthy individuals can appear as recurrent changes in compa...
Motivation: In the last years more than 20 vertebrate genomes have been sequenced, and the rate at which genomic DNA information becomes available is rapidly accelerating. Gene du...