By comparing genomes among both closely and distally related species, comparative genomics analysis characterizes structures and functions of different genomes in both conserved a...
Xinghuo Zeng, Matthew J. Nesbitt, Jian Pei, Ke Wan...
—The problem of reconstructing the duplication history of a set of tandemly repeated sequences was first introduced by Fitch [4]. Many recent studies deal with this problem, show...
Background: Paralog reduction, the loss of duplicate genes after whole genome duplication (WGD) is a pervasive process. Whether this loss proceeds gene by gene or through deletion...
We study two problems in the double cut and join (DCJ) model: sorting – transforming one multilinear genome into another and halving – transforming a duplicated genome into a p...
Evolutionary trees of species can be reconstructed by pairwise comparison of their entire genomes. Such a comparison can be quantified by determining the number of events that cha...