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» Genome rearrangements with duplications
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JCB
2007
78views more  JCB 2007»
14 years 9 months ago
Sorting by Reciprocal Translocations via Reversals Theory
The understanding of genome rearrangements is an important endeavor in comparative genomics. A major computational problem in this field is finding a shortest sequence of genome...
Michal Ozery-Flato, Ron Shamir
CSB
2005
IEEE
109views Bioinformatics» more  CSB 2005»
15 years 3 months ago
Patterns of Gene Deletion following Genome Duplication in Yeast
Whole genome duplication (WGD) is followed by massive duplicate deletion that reorganizes gene adjacencies. We compare the deletion patterns and adjacency reorganization following...
Jake K. Byrnes, Wen-Hsiung Li
RECOMB
2008
Springer
15 years 10 months ago
On Computing the Breakpoint Reuse Rate in Rearrangement Scenarios
In the past years, many combinatorial arguments have been made to support the theory that mammalian genome rearrangement scenarios rely heavily on breakpoint reuse. Different model...
Anne Bergeron, Julia Mixtacki, Jens Stoye
TCS
2008
14 years 9 months ago
A small trip in the untranquil world of genomes: A survey on the detection and analysis of genome rearrangement breakpoints
Genomes are dynamic molecules that are constantly undergoing mutations and rearrangements. The latter are large scale changes in a genome organisation that participate in the evol...
Claire Lemaitre, Marie-France Sagot
TCS
2008
14 years 9 months ago
Multi-break rearrangements and chromosomal evolution
Most genome rearrangements (e.g., reversals and translocations) can be represented as 2-breaks that break a genome at 2 points and glue the resulting fragments in a new order. Mul...
Max A. Alekseyev, Pavel A. Pevzner