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BMCBI
2010
142views more  BMCBI 2010»
14 years 9 months ago
Classification of protein sequences by means of irredundant patterns
Background: The classification of protein sequences using string algorithms provides valuable insights for protein function prediction. Several methods, based on a variety of diff...
Matteo Comin, Davide Verzotto
BMCBI
2006
157views more  BMCBI 2006»
14 years 9 months ago
Determination of the minimum number of microarray experiments for discovery of gene expression patterns
Background: One type of DNA microarray experiment is discovery of gene expression patterns for a cell line undergoing a biological process over a series of time points. Two import...
Fang-Xiang Wu, W. J. Zhang, Anthony J. Kusalik
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NAR
2008
115views more  NAR 2008»
14 years 9 months ago
Data growth and its impact on the SCOP database: new developments
The Structural Classification of Proteins (SCOP) database is a comprehensive ordering of all proteins of known structure, according to their evolutionary and structural relationsh...
Antonina Andreeva, Dave Howorth, John-Marc Chandon...
BMCBI
2010
134views more  BMCBI 2010»
14 years 9 months ago
R-Gada: a fast and flexible pipeline for copy number analysis in association studies
Background: Genome-wide association studies (GWAS) using Copy Number Variation (CNV) are becoming a central focus of genetic research. CNVs have successfully provided target genom...
Roger Pique-Regi, Alejandro Cáceres, Juan R...
BMCBI
2008
105views more  BMCBI 2008»
14 years 9 months ago
Novel computational methods for increasing PCR primer design effectiveness in directed sequencing
Background: Polymerase chain reaction (PCR) is used in directed sequencing for the discovery of novel polymorphisms. As the first step in PCR directed sequencing, effective PCR pr...
Kelvin Li, Anushka Brownley, Timothy B. Stockwell,...