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BMCBI
2010
88views more  BMCBI 2010»
14 years 9 months ago
Proteome scanning to predict PDZ domain interactions using support vector machines
Background: PDZ domains mediate protein-protein interactions involved in important biological processes through the recognition of short linear motifs in their target proteins. Tw...
Shirley Hui, Gary D. Bader
BMCBI
2008
158views more  BMCBI 2008»
14 years 9 months ago
Bioinformatics in Italy: BITS2007, the fourth annual meeting of the Italian Society of Bioinformatics
spectives. A total of 149 abstracts were accepted and presented in the poster session and 31 of them were selected for oral presentation. At the opening of the meeting, Roderic Gui...
Graziano Pesole, Manuela Helmer-Citterich
BMCBI
2008
158views more  BMCBI 2008»
14 years 9 months ago
VarDetect: a nucleotide sequence variation exploratory tool
Background: Single nucleotide polymorphisms (SNPs) are the most commonly studied units of genetic variation. The discovery of such variation may help to identify causative gene mu...
Chumpol Ngamphiw, Supasak Kulawonganunchai, Anunch...
BMCBI
2006
143views more  BMCBI 2006»
14 years 9 months ago
IsoSVM - Distinguishing isoforms and paralogs on the protein level
Background: Recent progress in cDNA and EST sequencing is yielding a deluge of sequence data. Like database search results and proteome databases, this data gives rise to inferred...
Michael Spitzer, Stefan Lorkowski, Paul Cullen, Al...
BMCBI
2007
148views more  BMCBI 2007»
14 years 9 months ago
fREDUCE: Detection of degenerate regulatory elements using correlation with expression
Background: The precision of transcriptional regulation is made possible by the specificity of physical interactions between transcription factors and their cognate binding sites ...
Randy Z. Wu, Christina Chaivorapol, Jiashun Zheng,...