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BMCBI
2005
178views more  BMCBI 2005»
14 years 9 months ago
A quantization method based on threshold optimization for microarray short time series
Background: Reconstructing regulatory networks from gene expression profiles is a challenging problem of functional genomics. In microarray studies the number of samples is often ...
Barbara Di Camillo, Fatima Sanchez-Cabo, Gianna To...
ILP
2005
Springer
15 years 3 months ago
Machine Learning for Systems Biology
In this paper we survey work being conducted at Imperial College on the use of machine learning to build Systems Biology models of the effects of toxins on biochemical pathways. Se...
Stephen Muggleton
BMCBI
2008
133views more  BMCBI 2008»
14 years 9 months ago
SPIKE - a database, visualization and analysis tool of cellular signaling pathways
Background: Biological signaling pathways that govern cellular physiology form an intricate web of tightly regulated interlocking processes. Data on these regulatory networks are ...
Ran Elkon, Rita Vesterman, Nira Amit, Igor Ulitsky...
BMCBI
2005
77views more  BMCBI 2005»
14 years 9 months ago
Ontological visualization of protein-protein interactions
Background: Cellular processes require the interaction of many proteins across several cellular compartments. Determining the collective network of such interactions is an importa...
Harold J. Drabkin, Christopher Hollenbeck, David P...
IJCNN
2007
IEEE
15 years 4 months ago
Branching Principal Components: Elastic Graphs, Topological Grammars and Metro Maps
— To approximate complex data, we propose new type of low-dimensional “principal object”: principal cubic complex. This complex is a generalization of linear and nonlinear pr...
Alexander N. Gorban, Neil R. Sumner, Andrei Yu. Zi...