—A comprehensive understanding of cancer progression may shed light on genetic and molecular mechanisms of oncogenesis, and it may provide much needed information for effective d...
Background: Natural antisense transcripts (NATs) are coding or non-coding RNAs with sequence complementarity to other transcripts (sense transcripts). These RNAs could potentially...
Biopathway databases have been developed, such as KEGG and EcoCyc, that compile interaction structures of biopathways together with biological annotations. However, these biopathw...
Background: One of the challenges of bioinformatics remains the recognition of short signal sequences in genomic DNA such as donor or acceptor splice sites, splicing enhancers or ...
Jens Keilwagen, Jan Grau, Stefan Posch, Ivo Grosse
Background: Phosphorylation events direct the flow of signals and metabolites along cellular protein networks. Current annotations of kinase-substrate binding events are far from ...