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» Genomic analysis of gene regulation complexity
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77
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BMCBI
2006
82views more  BMCBI 2006»
14 years 10 months ago
Transcriptomic response to differentiation induction
Background: Microarrays used for gene expression studies yield large amounts of data. The processing of such data typically leads to lists of differentially-regulated genes. A com...
G. W. Patton, Robert M. Stephens, I. A. Sidorov, X...
NAR
2006
170views more  NAR 2006»
14 years 10 months ago
The UCSC Genome Browser Database: update 2006
The University of California Santa Cruz Genome Browser Database (GBD) contains sequence and annotation data for the genomes of about a dozen vertebrate species and several major m...
Angela S. Hinrichs, Donna Karolchik, Robert Baerts...
55
Voted
BMCBI
2008
78views more  BMCBI 2008»
14 years 10 months ago
Genome Environment Browser (GEB): a dynamic browser for visualising high-throughput experimental data in the context of genome f
Background: There is accumulating evidence that the milieu of repeat elements and other nongenic sequence features at a given chromosomal locus, here defined as the genome environ...
Derek Huntley, Y. Amy Tang, Tatyana B. Nesterova, ...
129
Voted
BMCBI
2005
201views more  BMCBI 2005»
14 years 10 months ago
Principal component analysis for predicting transcription-factor binding motifs from array-derived data
Background: The responses to interleukin 1 (IL-1) in human chondrocytes constitute a complex regulatory mechanism, where multiple transcription factors interact combinatorially to...
Yunlong Liu, Matthew P. Vincenti, Hiroki Yokota
BMCBI
2007
147views more  BMCBI 2007»
14 years 10 months ago
Predicting combinatorial binding of transcription factors to regulatory elements in the human genome by association rule mining
Background: Cis-acting transcriptional regulatory elements in mammalian genomes typically contain specific combinations of binding sites for various transcription factors. Althoug...
Xochitl C. Morgan, Shulin Ni, Daniel P. Miranker, ...