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» Genomic analysis of gene regulation complexity
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BMCBI
2010
143views more  BMCBI 2010»
14 years 10 months ago
Learning gene regulatory networks from only positive and unlabeled data
Background: Recently, supervised learning methods have been exploited to reconstruct gene regulatory networks from gene expression data. The reconstruction of a network is modeled...
Luigi Cerulo, Charles Elkan, Michele Ceccarelli
94
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BMCBI
2010
111views more  BMCBI 2010»
14 years 10 months ago
Functional Analysis: Evaluation of Response Intensities - Tailoring ANOVA for Lists of Expression Subsets
Background: Microarray data is frequently used to characterize the expression profile of a whole genome and to compare the characteristics of that genome under several conditions....
Fabrice Berger, Bertrand De Meulder, Anthoula Gaig...
IJFCS
2008
49views more  IJFCS 2008»
14 years 10 months ago
A Markovian Approach for the Analysis of the gene Structure
Hidden Markov models (HMMs) are effective tools to detect series of statistically homogeneous structures, but they are not well suited to analyse complex structures. Numerous meth...
Christelle Melo de Lima, Laurent Gueguen, Christia...
82
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BIBE
2007
IEEE
129views Bioinformatics» more  BIBE 2007»
15 years 2 months ago
Statistial Analysis of nucleosome occupancy and histone modification data
Abstract-- In eukaryotic cells, genomic DNAs wrap around beadlike molecules, called nucleosomes, so as to pack more compactly in the nucleus of the cell. The nucleosome is made up ...
Guo-Cheng Yuan, Jun S. Liu
BMCBI
2010
101views more  BMCBI 2010»
14 years 10 months ago
Enrichment of homologs in insignificant BLAST hits by co-complex network alignment
Background: Homology is a crucial concept in comparative genomics. The algorithm probably most widely used for homology detection in comparative genomics, is BLAST. Usually a stri...
Like Fokkens, Sandra M. C. Botelho, Jos Boekhorst,...