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» Genomic analysis of gene regulation complexity
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BMCBI
2006
216views more  BMCBI 2006»
14 years 10 months ago
Machine learning approaches to supporting the identification of photoreceptor-enriched genes based on expression data
Background: Retinal photoreceptors are highly specialised cells, which detect light and are central to mammalian vision. Many retinal diseases occur as a result of inherited dysfu...
Haiying Wang, Huiru Zheng, David Simpson, Francisc...
WABI
2001
Springer
162views Bioinformatics» more  WABI 2001»
15 years 2 months ago
A Simple Hyper-Geometric Approach for Discovering Putative Transcription Factor Binding Sites
A central issue in molecular biology is understanding the regulatory mechanisms that control gene expression. The recent flood of genomic and postgenomic data opens the way for co...
Yoseph Barash, Gill Bejerano, Nir Friedman
91
Voted
BMCBI
2006
145views more  BMCBI 2006»
14 years 10 months ago
Fast-Find: A novel computational approach to analyzing combinatorial motifs
Background: Many vital biological processes, including transcription and splicing, require a combination of short, degenerate sequence patterns, or motifs, adjacent to defined seq...
Micah Hamady, Erin Peden, Rob Knight, Ravinder Sin...
83
Voted
BMCBI
2005
157views more  BMCBI 2005»
14 years 10 months ago
Statistical Viewer: a tool to upload and integrate linkage and association data as plots displayed within the Ensembl genome bro
Background: To facilitate efficient selection and the prioritization of candidate complex disease susceptibility genes for association analysis, increasingly comprehensive annotat...
Judith E. Stenger, Hong Xu, Carol Haynes, Elizabet...
BMCBI
2010
151views more  BMCBI 2010»
14 years 10 months ago
TF-finder: A software package for identifying transcription factors involved in biological processes using microarray data and e
Background: Identification of transcription factors (TFs) involved in a biological process is the first step towards a better understanding of the underlying regulatory mechanisms...
Xiaoqi Cui, Tong Wang, Huann-Sheng Chen, Victor Bu...