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» Genomic analysis of gene regulation complexity
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RECOMB
2005
Springer
15 years 10 months ago
RNA-RNA Interaction Prediction and Antisense RNA Target Search
Abstract. Recent studies demonstrating the existence of special non-coding "antisense" RNAs used in post-transcriptional gene regulation have received considerable attent...
Can Alkan, Emre Karakoç, Joseph H. Nadeau, ...
89
Voted
BMCBI
2007
146views more  BMCBI 2007»
14 years 10 months ago
Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data
Background: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental ...
Xiangdong Liu, Walter J. Jessen, Siva Sivaganesan,...
BMCBI
2010
90views more  BMCBI 2010»
14 years 10 months ago
PuTmiR: A database for extracting neighboring transcription factors of human microRNAs
Background: Some of the recent investigations in systems biology have revealed the existence of a complex regulatory network between genes, microRNAs (miRNAs) and transcription fa...
Sanghamitra Bandyopadhyay, Malay Bhattacharyya
BMCBI
2005
134views more  BMCBI 2005»
14 years 10 months ago
Inherited disorder phenotypes: controlled annotation and statistical analysis for knowledge mining from gene lists
Background: Analysis of inherited diseases and their associated phenotypes is of great importance to gain knowledge of underlying genetic interactions and could ultimately give cl...
Marco Masseroli, Osvaldo Galati, Mauro Manzotti, K...
BMCBI
2007
182views more  BMCBI 2007»
14 years 10 months ago
Identifying regulatory targets of cell cycle transcription factors using gene expression and ChIP-chip data
Background: ChIP-chip data, which indicate binding of transcription factors (TFs) to DNA regions in vivo, are widely used to reconstruct transcriptional regulatory networks. Howev...
Wei-Sheng Wu, Wen-Hsiung Li, Bor-Sen Chen