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» Genomic analysis of gene regulation complexity
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BMCBI
2008
93views more  BMCBI 2008»
14 years 10 months ago
Ranking single nucleotide polymorphisms by potential deleterious effects
Identifying single nucleotide polymorphisms (SNPs) that are responsible for common and complex diseases such as cancer is of major interest in current molecular epidemiology. Howe...
Phil Hyoun Lee, Hagit Shatkay
NAR
2007
124views more  NAR 2007»
14 years 9 months ago
The RNAz web server: prediction of thermodynamically stable and evolutionarily conserved RNA structures
Many non-coding RNA genes and cis-acting regulatory elements of mRNAs contain RNA secondary structures that are critical for their function. Such functional RNAs can be predicted ...
Andreas R. Gruber, Richard Neuböck, Ivo L. Ho...
BMCBI
2010
144views more  BMCBI 2010»
14 years 10 months ago
Finding sRNA generative locales from high-throughput sequencing data with NiBLS
Background: Next-generation sequencing technologies allow researchers to obtain millions of sequence reads in a single experiment. One important use of the technology is the seque...
Daniel MacLean, Vincent Moulton, David J. Studholm...
SCFBM
2008
107views more  SCFBM 2008»
14 years 9 months ago
Microbial Diagnostic Array Workstation (MDAW): a web server for diagnostic array data storage, sharing and analysis
Background: Microarrays are becoming a very popular tool for microbial detection and diagnostics. Although these diagnostic arrays are much simpler when compared to the traditiona...
Joy Scaria, Aswathy Sreedharan, Yung-Fu Chang
BMCBI
2005
122views more  BMCBI 2005»
14 years 10 months ago
FACT - a framework for the functional interpretation of high-throughput experiments
Background: Interpreting the results of high-throughput experiments, such as those obtained from DNA-microarrays, is an often time-consuming task due to the high number of data-po...
Felix Kokocinski, Nicolas Delhomme, Gunnar Wrobel,...