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» Genomic analysis of gene regulation complexity
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BMCBI
2007
149views more  BMCBI 2007»
14 years 10 months ago
Identification of tissue-specific cis-regulatory modules based on interactions between transcription factors
Background: Evolutionary conservation has been used successfully to help identify cis-acting DNA regions that are important in regulating tissue-specific gene expression. Motivate...
Xueping Yu, Jimmy J. Lin, Donald J. Zack, Jiang Qi...
WABI
2004
Springer
100views Bioinformatics» more  WABI 2004»
15 years 3 months ago
Reversing Gene Erosion - Reconstructing Ancestral Bacterial Genomes from Gene-Content and Order Data
In the last few years, it has become routine to use gene-order data to reconstruct phylogenies, both in terms of edge distances (parsimonious sequences of operations that transform...
Joel V. Earnest-DeYoung, Emmanuelle Lerat, Bernard...
BMCBI
2005
133views more  BMCBI 2005»
14 years 10 months ago
Ab initio identification of putative human transcription factor binding sites by comparative genomics
Background: Understanding transcriptional regulation of gene expression is one of the greatest challenges of modern molecular biology. A central role in this mechanism is played b...
Davide Corà, Carl Herrmann, Christoph Diete...
ISMB
1993
14 years 11 months ago
Pattern Discovery in Gene Regulation: Designing an Analysis Environment
Interactions that determinecellular fate are exceedingly complex, can take place at different levels of gene regulation and involve a large numberof components(such as genes, prot...
Stella Veretnik, Bruce R. Schatz
BMCBI
2007
120views more  BMCBI 2007»
14 years 10 months ago
Non-coding sequence retrieval system for comparative genomic analysis of gene regulatory elements
Background: Completion of the human genome sequence along with other species allows for greater understanding of the biochemical mechanisms and processes that govern healthy as we...
Sung Tae Doh, Yunyu Zhang, Matthew H. Temple, Li C...