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BMCBI
2010
150views more  BMCBI 2010»
14 years 7 months ago
Kernel based methods for accelerated failure time model with ultra-high dimensional data
Background: Most genomic data have ultra-high dimensions with more than 10,000 genes (probes). Regularization methods with L1 and Lp penalty have been extensively studied in survi...
Zhenqiu Liu, Dechang Chen, Ming Tan, Feng Jiang, R...
ICASSP
2007
IEEE
15 years 4 months ago
Evolutionary Sequence Modeling for Discovery of Peptide Hormones
There are currently a large number of ‘‘orphan’’ G-protein-coupled receptors (GPCRs) whose endogenous ligands (peptide hormones) are unknown. Identification of these pepti...
M. Kemal Sönmez, Lawrence Toll, Nina Zaveri
NAR
2011
225views Computer Vision» more  NAR 2011»
14 years 17 days ago
Gramene database in 2010: updates and extensions
Now in its 10th year, the Gramene database (http:// www.gramene.org) has grown from its primary focus on rice, the first fully-sequenced grass genome, to become a resource for maj...
Ken Youens-Clark, Edward S. Buckler, Terry M. Cass...
BMCBI
2005
114views more  BMCBI 2005»
14 years 9 months ago
Systematic analysis of human kinase genes: a large number of genes and alternative splicing events result in functional and stru
Background: Protein kinases are a well defined family of proteins, characterized by the presence of a common kinase catalytic domain and playing a significant role in many importa...
Luciano Milanesi, Mauro Petrillo, Leandra Sepe, An...
JCB
2000
129views more  JCB 2000»
14 years 9 months ago
Prediction of RNA Base Pairing Probabilities on Massively Parallel Computers
We present an implementation of McCaskill's algorithm for computing the base pair probabilities of an RNA molecule for massively parallel message passing architectures. The p...
Martin Fekete, Ivo L. Hofacker, Peter F. Stadler