Sciweavers

680 search results - page 75 / 136
» Genomic computing: explanatory modelling for functional geno...
Sort
View
ISMB
1997
14 years 11 months ago
Identifying Chimerism in Proteins Using Hidden Markov Models of Codon Usage
Protein chimerism is a phenomenon involving the combination of multiple ancestral sequences into a single, multi-domain protein through evolution. We propose a novel method for de...
Lawrence Hunter, Barry Zeeberg
BMCBI
2004
126views more  BMCBI 2004»
14 years 9 months ago
A probabilistic model for the evolution of RNA structure
Background: For the purposes of finding and aligning noncoding RNA gene- and cis-regulatory elements in multiple-genome datasets, it is useful to be able to derive multi-sequence ...
Ian Holmes
JCSS
2008
80views more  JCSS 2008»
14 years 9 months ago
Improved bounds on sorting by length-weighted reversals
We study the problem of sorting binary sequences and permutations by length-weighted reversals. We consider a wide class of cost functions, namely f( ) = for all 0, where is the...
Michael A. Bender, Dongdong Ge, Simai He, Haodong ...
BMCBI
2010
87views more  BMCBI 2010»
14 years 10 months ago
Epigenetic domains found in mouse embryonic stem cells via a hidden Markov model
Background: Epigenetics is an important layer of transcriptional control necessary for cell-type specific gene regulation. Recent studies have shown significant epigenetic pattern...
Jessica L. Larson, Guo-Cheng Yuan
COCOON
2005
Springer
15 years 3 months ago
Perfect Sorting by Reversals
In computational biology, gene order data is often modelled as signed permutations. A classical problem in genome comparison is to detect conserved segments in a permutation, that ...
Marie-France Sagot, Eric Tannier